A Pilot Study to Assess Food Safety and Potential Cholesterol-Lowering Efficacy of Antrodia cinnamomea Solid-State Cultivated Mycelium in Healthy Adults

Authors: Wan-Jing Chen and Fung-Wei Chang

Journal: Evidence-Based Complementary and Alternative Medicine

Study Design: Open-label, single-arm study

Participants: 32 healthy adults

Trial Length: 3 months with a 1-month follow-up

Intervention:

• Ingestion of Antrodia cinnamomea solid-state cultivated mycelium (LAC) capsules twice a day

Outcome Measures:

• Fasting blood glucose
• Blood pressure
• Triglyceride levels
• Liver and renal function indices
• Total cholesterol levels
• Adverse events

Summary:

This study investigated the safety and potential cholesterol-lowering effects of LAC in healthy adults. Participants consumed LAC capsules for three months, and their physiological parameters were monitored during the study and for one month after the end-point. The results showed that LAC consumption did not significantly change fasting blood glucose, blood pressure, triglyceride levels, or liver and renal function indices. No adverse events were reported during the trial. However, there was a significant decrease in total cholesterol levels, with men and women experiencing reductions of 5.7% and 5.3%, respectively. The study concluded that LAC consumption is safe and has the potential to reduce total cholesterol in healthy adults.   Sources and related content