Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients.

Authors: S Takashima, Y Kinami, I Miyazaki

Journal: Gan To Kagaku Ryoho

Study Design: Randomized controlled trial

Primary Outcomes: 5-year survival rates

Participants: 124 patients with colorectal cancer who underwent curative surgery

Intervention:

All patients received Mitomycin post-surgery

Group A (71 patients): FT-207 suppositories for one year

Group B (53 patients): PSK orally for one year

Summary: The study suggested that PSK might be effective in prolonging survival in colorectal cancer patients after curative surgery, with Group B (PSK) showing consistently higher survival rates than Group A (FT-207), although the difference was not statistically significant. The number of recurrences within two years also tended to be lower in the PSK group.

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