The Role of Ganoderma Lucidum Uptake on Some Hematological and Immunological Response in Patients with Coronavirus (COVID-19)

Authors: Miqdam M. Obaid AL-jumaili, Fahad K. Y. Al-dulaimi, Mohammed A. Ajeel

Journal: Systematic Reviews in Pharmacy

Study Design:

• Intervention: Oral Ganoderma lucidum (G. lucidum) or Human convalescent plasma or both or neither
• Participants: 150 patients with COVID-19, ages 35-55
• Duration: April-June 2020
• Outcome Measures:
  • Immunoglobulin (IgG and IgM) levels
  • Total and differential white blood cell counts
  • Hemoglobin (Hb), packed cell volume (PCV), red blood cell (RBC) count, and platelet count

Summary: This study investigated the effects of G. lucidum on hematological and immunological responses in patients with COVID-19. The results showed that G. lucidum, alone or in combination with convalescent plasma, may help improve immune response and reduce the negative impact of COVID-19 on blood parameters. Specifically, G. lucidum was associated with increased levels of IgG antibodies and certain white blood cells, while decreasing markers of inflammation. Additionally, G. lucidum helped to mitigate the reduction in hemoglobin, red blood cells, and platelets caused by COVID-19. These findings suggest that G. lucidum may be a potential adjunctive therapy for COVID-19.