Randomized Double-blind Placebo-controlled Clinical Trial and Assessment of Fermentation Product of Cordyceps Sinensis (Cs-4) in Enhancing Aerobic Capacity and Respiratory Function of The Healthy Elderly Volunteers

Authors: Xiao Yi, Huang Xizhen, Zhu Jiashi

Journal: Chinese Journal of Integrated Traditional and Western Medicine

Study Design: Randomized, double-blind, placebo-controlled trial

Participants: 37 healthy, elderly subjects

Intervention: Cs-4 (fermentation product of Ophiocordyceps sinensis) or placebo for 6 weeks

Outcome Measures:

• Exercise performance (VO2max, VO2 at anaerobic threshold)
• Ventilation

Summary: The study found that Cs-4 supplementation significantly increased VO2max and VO2 at anaerobic threshold in elderly subjects, suggesting that it may improve aerobic capacity and exercise performance.