The Efficacy of Ganoderma lucidum in Overweight Individuals: A Randomized Placebo-controlled trial

Authors: Shilan Babamiri, Mansooreh Sadat Mojani Qomi, Maryam Shiehmorteza

Journal: Mediterranean Journal of Nutrition and Metabolism

Study Design:

• Intervention: 3 capsules of Ganoderma lucidum per day (each containing 220 mg of whole powder and 30 mg of pure aqueous extract) or placebo
• Participants: 72 (36 in the treatment group and 33 in the placebo group)
• Duration: 6 weeks
• Outcome Measures:
  • Anthropometric indices (body weight, body mass index [BMI], waist circumference [WC], mid-upper arm circumference [MAUC], hip circumference, waist-hip ratio)
  • Fasting blood sugar (FBS)
  • Lipid profile (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides)
  • Blood pressure

Summary: This study investigated the effects of Ganoderma lucidum supplementation on weight and metabolic parameters in overweight individuals. After 6 weeks, the treatment group showed significant reductions in body weight, BMI, waist circumference, and mid-upper arm circumference compared to the placebo group. Additionally, the treatment group had significant improvements in total cholesterol and LDL-cholesterol levels. There were no significant changes in other measures like hip circumference, waist-hip ratio, fasting blood sugar, HDL-cholesterol, triglycerides, or blood pressure.